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B12 increases energy and metabolic rate while supporting weight loss, but it's most effective when combined with proper diet, exercise, and stress management rather than used as a standalone solution

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CagriSema produced mean weight loss of 13.7% at 68 weeks compared to 3.4% with placebo, and 73.5% of CagriSema-treated participants achieved HbA1c of 6.5% or below compared to 15.9% with placebo